Product Data Sheet
Antibiofilm agent-12
Catalog No. A27609
Antibiofilm agent-12 is a carbazate derivative with a primary mechanism as an antifungal agent targeting Candida auris. It exhibits significant antifungal activity, demonstrated by a minimum inhibitory concentration (MIC90) of 237.9 μM, and functions by disrupting drug efflux pump activity and promoting ergosterol depletion. This effectively hinders biofilm formation and decreases the metabolic flexibility of Candida auris. Furthermore, Antibiofilm agent-12 has shown efficacy in a C. elegans model infected with Candida auris, highlighting its potential for addressing fungal infections and biofilm-related complications.
Chemical Information
| Catalog Num | A27609 |
|---|---|
| M. Wt | 262.69 |
| Formula | C13H11ClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 480452-24-2 |
| Synonyms | |
| SMILES | O=C(NNC1=CC=C(Cl)C=C1)OC2=CC=CC=C2 |
Biological Activity
| Description | Antibiofilm agent-12 is a carbazate derivative with a primary mechanism as an antifungal agent targeting Candida auris. It exhibits significant antifungal activity, demonstrated by a minimum inhibitory concentration (MIC90) of 237.9 μM, and functions by disrupting drug efflux pump activity and promoting ergosterol depletion. This effectively hinders biofilm formation and decreases the metabolic flexibility of Candida auris. Furthermore, Antibiofilm agent-12 has shown efficacy in a C. elegans model infected with Candida auris, highlighting its potential for addressing fungal infections and biofilm-related complications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
