Product Data Sheet
Temporin-SHa
Catalog No. A27646
Temporin-SHa is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, effectively targeting both Gram-positive and Gram-negative bacteria, including drug-resistant strains. With a minimum inhibitory concentration (MIC) of 6.25 μM against Listeria ivanovii and 10 μM against Escherichia coli, it is also active against fungal pathogens such as Candida albicans (MIC = 25 μM) and Saccharomyces cerevisiae (MIC = 12 μM). Furthermore, Temporin-SHa demonstrates efficacy against protozoan parasites, including Leishmania infantum and Trypanosoma cruzi, and exhibits antiviral activity against HSV-1, alongside anti-cancer properties that include cytotoxicity against breast cancer (MCF-7) and lung cancer (H460) cell lines.
Chemical Information
| Catalog Num | A27646 |
|---|---|
| M. Wt | 1380.74 |
| Formula | C67H109N15O14S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1065010-73-2 |
| Synonyms | |
| SMILES | [C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CC(C)C)=O)CO)=O)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCSC)=O)CC(C)C)=O)=O)CCCCN)=O)(C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)CC(C)C |
Biological Activity
| Description | Temporin-SHa is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, effectively targeting both Gram-positive and Gram-negative bacteria, including drug-resistant strains. With a minimum inhibitory concentration (MIC) of 6.25 μM against Listeria ivanovii and 10 μM against Escherichia coli, it is also active against fungal pathogens such as Candida albicans (MIC = 25 μM) and Saccharomyces cerevisiae (MIC = 12 μM). Furthermore, Temporin-SHa demonstrates efficacy against protozoan parasites, including Leishmania infantum and Trypanosoma cruzi, and exhibits antiviral activity against HSV-1, alongside anti-cancer properties that include cytotoxicity against breast cancer (MCF-7) and lung cancer (H460) cell lines. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
