Product Data Sheet

Oxiconazole

Catalog No. A27674

main product photo
Oxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research.
Chemical Information
Catalog NumA27674
M. Wt429.13
FormulaC18H13Cl4N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.64211-45-6
SynonymsRo 13-8996 free base
SMILESClC1=CC=C(/C(CN2C=CN=C2)=N/OCC3=CC=C(Cl)C=C3Cl)C(Cl)=C1
Biological Activity
DescriptionOxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research.
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