Product Data Sheet

SDH-IN-25

Catalog No. A27677

main product photo
SDH-IN-25 is a selective inhibitor of succinate dehydrogenase (SDH), with an IC50 value of 4.82 mg/L. This compound displays significant antifungal activity by disrupting respiratory metabolism through its binding to complex II, consequently inducing hyphal morphology changes, generating reactive oxygen species (ROS), and affecting mitochondrial membrane potential (MMP) in fungal mycelia. SDH-IN-25 is suitable for research applications focused on agricultural disease management and the development of novel antifungal strategies.
Chemical Information
Catalog NumA27677
M. Wt486.14
FormulaC19H15BrCl2N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3052432-15-9
Synonyms
SMILESClC1=CC(Cl)=C(OCC(NNC2=CC=C(Br)C=C2)=O)C(C3OC(C(C3)=C)=O)=C1
Biological Activity
DescriptionSDH-IN-25 is a selective inhibitor of succinate dehydrogenase (SDH), with an IC50 value of 4.82 mg/L. This compound displays significant antifungal activity by disrupting respiratory metabolism through its binding to complex II, consequently inducing hyphal morphology changes, generating reactive oxygen species (ROS), and affecting mitochondrial membrane potential (MMP) in fungal mycelia. SDH-IN-25 is suitable for research applications focused on agricultural disease management and the development of novel antifungal strategies.
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SHIPPING AND STORAGE
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