Antibacterial agent 129
Catalog No. A27760

Antibacterial agent 129 is an oxetanyl-quinoline derivative that exhibits potent antibacterial activity targeting Pseudomonas mirabilis and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25 μM and 31.5 μM, respectively. Additionally, it demonstrates significant antifungal activity against Aspergillus niger, also with an MIC of 31.25 μM. Notably, Antibacterial agent 129 displays excellent antimycobacterial properties, with an MIC of 57.73 μM against Mycobacterium tuberculosis H37Rv. This compound can be utilized in pharmaceutical research to explore new antibacterial and antifungal therapies.
Chemical Information
| Catalog Num | A27760 |
|---|---|
| M. Wt | 433.45 |
| Formula | C26H21F2NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2874263-66-6 |
| Synonyms | |
| SMILES | CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC=CC=C5)F |
Biological Activity
| Description | Antibacterial agent 129 is an oxetanyl-quinoline derivative that exhibits potent antibacterial activity targeting Pseudomonas mirabilis and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25 μM and 31.5 μM, respectively. Additionally, it demonstrates significant antifungal activity against Aspergillus niger, also with an MIC of 31.25 μM. Notably, Antibacterial agent 129 displays excellent antimycobacterial properties, with an MIC of 57.73 μM against Mycobacterium tuberculosis H37Rv. This compound can be utilized in pharmaceutical research to explore new antibacterial and antifungal therapies. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


