Product Data Sheet
Propiconazole-d3 nitrate
Catalog No. A27857
Propiconazole-d3 nitrate is a deuterium-labeled analog of propiconazole, acting primarily as a triazole fungicide. It targets the enzymatic conversion of lanosterol to ergosterol, crucial for fungal cell membrane integrity. This compound exhibits inhibitory effects on Saccharomyces cerevisiae, while showing significantly lower impact on rat liver microsomal cytochrome P450, with reported IC50 values of 0.04 µM and >200 µM, respectively. Propiconazole-d3 nitrate has demonstrated efficacy against Trichophyton deformans and Rhizopus stolonifer, with ED50 values of 0.073 µg/mL and 4.6 µg/mL, respectively, and is known to enhance the production of reactive oxygen species (ROS), making it a valuable tool in fungal research and studies related to oxidative stress.
Chemical Information
| Catalog Num | A27857 |
|---|---|
| M. Wt | 408.25 |
| Formula | C15H15D3Cl2N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2699607-26-4 |
| Synonyms | |
| SMILES | ClC1=CC(Cl)=C(C2(OC([2H])(C([2H])(O2)CCC)[2H])CN3C=NC=N3)C=C1.O=[N+]([O-])O |
Biological Activity
| Description | Propiconazole-d3 nitrate is a deuterium-labeled analog of propiconazole, acting primarily as a triazole fungicide. It targets the enzymatic conversion of lanosterol to ergosterol, crucial for fungal cell membrane integrity. This compound exhibits inhibitory effects on Saccharomyces cerevisiae, while showing significantly lower impact on rat liver microsomal cytochrome P450, with reported IC50 values of 0.04 µM and >200 µM, respectively. Propiconazole-d3 nitrate has demonstrated efficacy against Trichophyton deformans and Rhizopus stolonifer, with ED50 values of 0.073 µg/mL and 4.6 µg/mL, respectively, and is known to enhance the production of reactive oxygen species (ROS), making it a valuable tool in fungal research and studies related to oxidative stress. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
