Product Data Sheet
Antifungal agent 30
Catalog No. A27861
Antifungal agent 30 (compound A18) is a potent antifungal compound that targets cytochrome P450 51 (CYP51). It demonstrates significant antifungal activity against Candida albicans and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.03 and 0.5 μg/mL, respectively. This agent is particularly effective against fluconazole-resistant strains, making it a valuable tool for research in antifungal drug development and resistance mechanisms. The activity of Antifungal agent 30 is primarily attributed to its hydrogen and coordination bond interactions with CYP51.
Chemical Information
| Catalog Num | A27861 |
|---|---|
| M. Wt | 446.18 |
| Formula | C18H14Cl2F2N2Se |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2422019-91-6 |
| Synonyms | |
| SMILES | FC1=CC(F)=C(C=C1)C([Se]CC2=C(C=C(C=C2)Cl)Cl)CN3C=CN=C3 |
Biological Activity
| Description | Antifungal agent 30 (compound A18) is a potent antifungal compound that targets cytochrome P450 51 (CYP51). It demonstrates significant antifungal activity against Candida albicans and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.03 and 0.5 μg/mL, respectively. This agent is particularly effective against fluconazole-resistant strains, making it a valuable tool for research in antifungal drug development and resistance mechanisms. The activity of Antifungal agent 30 is primarily attributed to its hydrogen and coordination bond interactions with CYP51. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
