(Rac)-NPD6433
Catalog No. A27957

(Rac)-NPD6433 is a Fas1 inhibitor targeting the enoyl reductase domain of fatty acid synthase 1. As a triazenyl indole, it demonstrates broad-spectrum antifungal activity against various screening fungal strains. By covalently inhibiting flavin mononucleotide-dependent NADPH-oxidation activity, (Rac)-NPD6433 effectively disrupts essential fatty acid biosynthesis, making it a valuable tool for research in fungal metabolism and potential therapeutic applications.
Chemical Information
| Catalog Num | A27957 |
|---|---|
| M. Wt | 391.42 |
| Formula | C21H21N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 895908-81-3 |
| Synonyms | |
| SMILES | O=C(C1=C(/N=N/N2CC3C4=CC=CC(N4CC(C3)C2)=O)C5=C(C=CC=C5)N1)OC |
Biological Activity
| Description | (Rac)-NPD6433 is a Fas1 inhibitor targeting the enoyl reductase domain of fatty acid synthase 1. As a triazenyl indole, it demonstrates broad-spectrum antifungal activity against various screening fungal strains. By covalently inhibiting flavin mononucleotide-dependent NADPH-oxidation activity, (Rac)-NPD6433 effectively disrupts essential fatty acid biosynthesis, making it a valuable tool for research in fungal metabolism and potential therapeutic applications. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


