Product Data Sheet

SC-58272

Catalog No. A28021

main product photo
SC-58272 is a potent and selective inhibitor of N-myristoyltransferase (Nmt) in Candida albicans, exhibiting an IC50 of 56 nM against the strain B311. This compound demonstrates a 250-fold selectivity for the fungal enzyme when compared to the human counterpart. SC-58272 is valuable for research applications involving fungal pathogenesis and the study of myristoylation processes in C. albicans.
Chemical Information
Catalog NumA28021
M. Wt596.80
FormulaC33H52N6O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.164931-25-3
Synonyms
SMILESO=C(NCCC1CCCCC1)[C@H](CCCCN)NC([C@H](CO)NC(CC2=CC=C(C=C2)CCCCN3C(C)=NC=C3)=O)=O
Biological Activity
DescriptionSC-58272 is a potent and selective inhibitor of N-myristoyltransferase (Nmt) in Candida albicans, exhibiting an IC50 of 56 nM against the strain B311. This compound demonstrates a 250-fold selectivity for the fungal enzyme when compared to the human counterpart. SC-58272 is valuable for research applications involving fungal pathogenesis and the study of myristoylation processes in C. albicans.
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