Product Data Sheet
Ketoconazole-d8
Catalog No. A28264
Ketoconazole-d8 is a deuterated analogue of the antifungal agent Ketoconazole, which primarily targets the cytochrome P450 enzymes CYP3A4 and CYP24A1. This stable isotope-labeled compound is valuable for metabolic and pharmacokinetic studies, providing insights into the drug's biochemical pathways. Its unique labeling enables precise tracking in various biological assays, facilitating advanced research in pharmacology and toxicology.
Chemical Information
| Catalog Num | A28264 |
|---|---|
| M. Wt | 539.48 |
| Formula | C26H20D8Cl2N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217706-96-1 |
| Synonyms | |
| SMILES | CC(N(C([2H])([2H])C1([2H])[2H])C([2H])([2H])C([2H])([2H])N1C(C=C2)=CC=C2OC[C@@H](CO3)O[C@]3(C4=C(C=C(C=C4)Cl)Cl)CN5C=CN=C5)=O |
Biological Activity
| Description | Ketoconazole-d8 is a deuterated analogue of the antifungal agent Ketoconazole, which primarily targets the cytochrome P450 enzymes CYP3A4 and CYP24A1. This stable isotope-labeled compound is valuable for metabolic and pharmacokinetic studies, providing insights into the drug's biochemical pathways. Its unique labeling enables precise tracking in various biological assays, facilitating advanced research in pharmacology and toxicology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
