Polycarpine hydrochloride
Catalog No. A28266

Polycarpine hydrochloride is a potent inhibitor of the main protease (Mpro) with an IC50 of 30 nM, making it a valuable anti-coronaviral agent. This compound, derived from Polycarpa aurata, exhibits significant antiviral properties, demonstrating effectiveness against SARS-CoV-2 Mpro and PEDV Mpro, with IC50 values of 30.0 nM and 0.12 μM respectively. It also possesses antifungal activity, positioning it as a versatile tool for research in virology and infectious diseases.
Chemical Information
| Catalog Num | A28266 |
|---|---|
| M. Wt | 541.52 |
| Formula | C22H26Cl2N6O2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 175669-29-1 |
| Synonyms | |
| SMILES | COC1=CC=C(C=C1)C2=C(N(C(N)=N2)C)SSC3=C(N=C(N3C)N)C4=CC=C(C=C4)OC.Cl.Cl |
Biological Activity
| Description | Polycarpine hydrochloride is a potent inhibitor of the main protease (Mpro) with an IC50 of 30 nM, making it a valuable anti-coronaviral agent. This compound, derived from Polycarpa aurata, exhibits significant antiviral properties, demonstrating effectiveness against SARS-CoV-2 Mpro and PEDV Mpro, with IC50 values of 30.0 nM and 0.12 μM respectively. It also possesses antifungal activity, positioning it as a versatile tool for research in virology and infectious diseases. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


