Product Data Sheet

Abafungin

Catalog No. A28364

main product photo
Abafungin is an antifungal agent that functions by inhibiting the transmethylation at the C-24 position of the sterol side chain, a reaction catalyzed by the enzyme sterol-C-24-methyltransferase. This mechanistic action disrupts ergosterol biosynthesis, which is crucial for fungal cell membrane integrity. Abafungin is used in research to study fungal pathogenesis and to develop new antifungal therapies.
Chemical Information
Catalog NumA28364
M. Wt378.49
FormulaC21H22N4OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129639-79-8
SynonymsBAY-W-6341
SMILESCC1=CC(C)=C(OC2=CC=CC=C2C3=CSC(NC4=NCCCN4)=N3)C=C1
Biological Activity
DescriptionAbafungin is an antifungal agent that functions by inhibiting the transmethylation at the C-24 position of the sterol side chain, a reaction catalyzed by the enzyme sterol-C-24-methyltransferase. This mechanistic action disrupts ergosterol biosynthesis, which is crucial for fungal cell membrane integrity. Abafungin is used in research to study fungal pathogenesis and to develop new antifungal therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.