1-Monomyristin
Catalog No. A28465

1-Monomyristin serves as a dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), with IC50 values of 18 μM and 32 μM, respectively. It effectively inhibits the hydrolysis of 2-oleoylglycerol via MAGL, exhibiting antibacterial and antifungal activities against pathogens such as Staphylococcus aureus, Aggregatibacter actinomycetemcomitans, and Candida albicans. Additionally, 1-Monomyristin demonstrates lethality to brine shrimp and shows marginal cytotoxicity against prostate cancer cells. This reagent is suitable for research focused on bacterial and fungal infections, as well as various cancer types, including renal cancer, prostate adenocarcinoma, and pancreatic cancer.
Chemical Information
| Catalog Num | A28465 |
|---|---|
| M. Wt | 302.45 |
| Formula | C17H34O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 589-68-4 |
| Synonyms | |
| SMILES | CCCCCCCCCCCCCC(OCC(O)CO)=O |
Biological Activity
| Description | 1-Monomyristin serves as a dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), with IC50 values of 18 μM and 32 μM, respectively. It effectively inhibits the hydrolysis of 2-oleoylglycerol via MAGL, exhibiting antibacterial and antifungal activities against pathogens such as Staphylococcus aureus, Aggregatibacter actinomycetemcomitans, and Candida albicans. Additionally, 1-Monomyristin demonstrates lethality to brine shrimp and shows marginal cytotoxicity against prostate cancer cells. This reagent is suitable for research focused on bacterial and fungal infections, as well as various cancer types, including renal cancer, prostate adenocarcinoma, and pancreatic cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


