Product Data Sheet

SDH-IN-1

Catalog No. A28498

main product photo
SDH-IN-1 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 4.53 μM. This compound demonstrates significant antifungal properties, particularly effective against S. sclerotiorum with an EC50 of 0.14 mg/L. SDH-IN-1 is a valuable tool for researchers studying fungal pathogenesis and metabolism, providing insights into SDH's role in cellular respiration and therapeutic strategies against fungal infections.
Chemical Information
Catalog NumA28498
M. Wt354.21
FormulaC14H9Cl2N3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2685795-52-0
Synonyms
SMILESO=C(C1=NN=C(C2=CC=CS2)O1)NCC3=CC=C(Cl)C(Cl)=C3
Biological Activity
DescriptionSDH-IN-1 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 4.53 μM. This compound demonstrates significant antifungal properties, particularly effective against S. sclerotiorum with an EC50 of 0.14 mg/L. SDH-IN-1 is a valuable tool for researchers studying fungal pathogenesis and metabolism, providing insights into SDH's role in cellular respiration and therapeutic strategies against fungal infections.
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