Product Data Sheet
ZM-306416 hydrochloride
Catalog No. A28595
ZM-306416 hydrochloride is a potent inhibitor of vascular endothelial growth factor receptor (VEGFR), demonstrating IC50 values of 0.1 μM for KDR and 2 μM for Flt. In addition, it functions as an epidermal growth factor receptor (EGFR) inhibitor with an IC50 of less than 10 nM. This dual inhibition profile makes ZM-306416 hydrochloride valuable for research in cancer biology and angiogenesis, providing insights into tumor growth and vascular development mechanisms.
Chemical Information
| Catalog Num | A28595 |
|---|---|
| M. Wt | 370.21 |
| Formula | C16H14Cl2FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 196603-47-1 |
| Synonyms | |
| SMILES | FC1=CC(Cl)=CC=C1NC2=C3C=C(OC)C(OC)=CC3=NC=N2.Cl |
Biological Activity
| Description | ZM-306416 hydrochloride is a potent inhibitor of vascular endothelial growth factor receptor (VEGFR), demonstrating IC50 values of 0.1 μM for KDR and 2 μM for Flt. In addition, it functions as an epidermal growth factor receptor (EGFR) inhibitor with an IC50 of less than 10 nM. This dual inhibition profile makes ZM-306416 hydrochloride valuable for research in cancer biology and angiogenesis, providing insights into tumor growth and vascular development mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
