Product Data Sheet

AST5902 mesylate

Catalog No. A28643

main product photo
AST5902 mesylate is a potent EGFR inhibitor that demonstrates significant antineoplastic activity. As a principal metabolite of Alflutinib, it plays a crucial role in the treatment of non-small cell lung cancer, effectively targeting activating EGFR mutations. Additionally, AST5902 mesylate shows promise in overcoming resistance associated with the EGFR T790M mutation, making it a valuable tool for cancer research and therapeutic development.
Chemical Information
Catalog NumA28643
M. Wt650.67
FormulaC28H33F3N8O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2412155-75-8
Synonyms
SMILESC=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(C)CCNC)=O.O=S(O)(C)=O
Biological Activity
DescriptionAST5902 mesylate is a potent EGFR inhibitor that demonstrates significant antineoplastic activity. As a principal metabolite of Alflutinib, it plays a crucial role in the treatment of non-small cell lung cancer, effectively targeting activating EGFR mutations. Additionally, AST5902 mesylate shows promise in overcoming resistance associated with the EGFR T790M mutation, making it a valuable tool for cancer research and therapeutic development.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.