Product Data Sheet
EGFR-IN-126
Catalog No. A28670
EGFR-IN-126 is a potent inhibitor targeting the EGFRL858R/T790M/C797S mutations, exhibiting an IC50 value of 0.005 μM. This compound demonstrates significant antitumor activity in both in vivo and in vitro models, making it a valuable tool for cancer research and therapeutic development focusing on EGFR-related malignancies.
Chemical Information
| Catalog Num | A28670 |
|---|---|
| M. Wt | 567.45 |
| Formula | C28H28BrFN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2890621-88-0 |
| Synonyms | |
| SMILES | COC1=C(OCC2CCN(C)CC2)C=C(N=CN=C3NC4=CC=C(OC5=CC=CC=C5F)C(Br)=C4)C3=C1 |
Biological Activity
| Description | EGFR-IN-126 is a potent inhibitor targeting the EGFRL858R/T790M/C797S mutations, exhibiting an IC50 value of 0.005 μM. This compound demonstrates significant antitumor activity in both in vivo and in vitro models, making it a valuable tool for cancer research and therapeutic development focusing on EGFR-related malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
