Product Data Sheet
ODS-2004436
Catalog No. A28675
ODS-2004436 is a small molecule radiotracer that targets the epidermal growth factor receptor (EGFR) for use in positron emission tomography (PET) imaging. This compound exhibits significantly higher uptake in xenograft models of lung cancer harboring EGFR mutations compared to wild-type models, enabling effective differentiation of mutation status. ODS-2004436 is valuable for identifying EGFR-positive tumors and predicting therapeutic responses, particularly in non-small cell lung cancer (NSCLC) research applications.
Chemical Information
| Catalog Num | A28675 |
|---|---|
| M. Wt | 528.99 |
| Formula | C26H29Cl18FN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2130982-18-0 |
| Synonyms | |
| SMILES | ClC1=CC(NC2=NC=NC3=CC(OCC[18F])=C(OCCCNC([C@@H](C(C)C)N4)=O)C=C23)=C(CC4=O)C=C1 |
Biological Activity
| Description | ODS-2004436 is a small molecule radiotracer that targets the epidermal growth factor receptor (EGFR) for use in positron emission tomography (PET) imaging. This compound exhibits significantly higher uptake in xenograft models of lung cancer harboring EGFR mutations compared to wild-type models, enabling effective differentiation of mutation status. ODS-2004436 is valuable for identifying EGFR-positive tumors and predicting therapeutic responses, particularly in non-small cell lung cancer (NSCLC) research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
