Product Data Sheet

EGFRvIII peptide (PEPvIII)

Catalog No. A28698

main product photo
EGFRvIII peptide (PEPvIII) is a tumor-specific mutation predominantly expressed in glioblastoma multiforme (GBM) and various other neoplasms, significantly contributing to enhanced tumorigenicity. This peptide serves as a valuable target for the development of antitumor immunotherapies, allowing for the potential targeting of cancer cells while sparing normal tissues. Its specific expression profile makes it a crucial tool for research into GBM and other malignancies.
Chemical Information
Catalog NumA28698
M. Wt1634.81
FormulaC70H111N19O24S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129112-17-0
Synonyms
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCCN)=O)CCCCN)=O)=O)CC(N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(O)=O)CS)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)C(C)C)=O
Biological Activity
DescriptionEGFRvIII peptide (PEPvIII) is a tumor-specific mutation predominantly expressed in glioblastoma multiforme (GBM) and various other neoplasms, significantly contributing to enhanced tumorigenicity. This peptide serves as a valuable target for the development of antitumor immunotherapies, allowing for the potential targeting of cancer cells while sparing normal tissues. Its specific expression profile makes it a crucial tool for research into GBM and other malignancies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.