Product Data Sheet
IGF-1R modulator 1
Catalog No. A28700
IGF-1R modulator 1 is a selective modulator of the insulin-like growth factor 1 receptor (IGF-1R), exhibiting EC50 values of 0.25 μM for IGF-1R, alongside notable activity against FGFR1, TrkA, and TrkB. This compound is valuable in the study of pathological conditions associated with dysregulated signaling of neurotrophins and trophic factors, including Alzheimer's disease. Its efficacy in modulating IGF-1R offers potential insights into therapeutic approaches for neurodegenerative disorders.
Chemical Information
| Catalog Num | A28700 |
|---|---|
| M. Wt | 387.39 |
| Formula | C22H17N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2375424-89-6 |
| Synonyms | |
| SMILES | O=C1NC(N(C(N1C2=CC=CC=C2)=O)C3=CC=C(C(C)=C3)OC4=CC=CC=C4)=O |
Biological Activity
| Description | IGF-1R modulator 1 is a selective modulator of the insulin-like growth factor 1 receptor (IGF-1R), exhibiting EC50 values of 0.25 μM for IGF-1R, alongside notable activity against FGFR1, TrkA, and TrkB. This compound is valuable in the study of pathological conditions associated with dysregulated signaling of neurotrophins and trophic factors, including Alzheimer's disease. Its efficacy in modulating IGF-1R offers potential insights into therapeutic approaches for neurodegenerative disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
