Product Data Sheet

Gefitinib impurity 2

Catalog No. A28725

main product photo
Gefitinib impurity 2 is an impurity of the EGFR tyrosine kinase inhibitor, Gefitinib. While Gefitinib exhibits potent and selective inhibition of EGFR with an IC50 of 33 nM, this impurity may be relevant for studies focused on the characterization and validation of Gefitinib-related compounds. Research applications primarily include analytical chemistry and quality control in the synthesis of Gefitinib. Additionally, the impurity may provide insights into the pharmacological behavior and metabolic pathway analysis of EGFR inhibitors.
Chemical Information
Catalog NumA28725
M. Wt309.37
FormulaC15H23N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.246512-44-7
Synonyms
SMILESO=C(N)C1=CC(OCCCN2CCOCC2)=C(OC)C=C1N
Biological Activity
DescriptionGefitinib impurity 2 is an impurity of the EGFR tyrosine kinase inhibitor, Gefitinib. While Gefitinib exhibits potent and selective inhibition of EGFR with an IC50 of 33 nM, this impurity may be relevant for studies focused on the characterization and validation of Gefitinib-related compounds. Research applications primarily include analytical chemistry and quality control in the synthesis of Gefitinib. Additionally, the impurity may provide insights into the pharmacological behavior and metabolic pathway analysis of EGFR inhibitors.
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