Product Data Sheet

EGFR-IN-71

Catalog No. A28770

main product photo
EGFR-IN-71 is a potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 value of 3.7 μM. This compound is particularly useful in research focused on chordoma, providing a tool for studying EGFR-related signaling pathways. Additionally, EGFR-IN-71 features an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling diverse applications in chemical biology and bioconjugation studies.
Chemical Information
Catalog NumA28770
M. Wt405.62
FormulaC16H9ClIN3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2676155-98-7
Synonyms
SMILESIC1=CC2=NC=NC(NC3=CC=C(Cl)C(C#C)=C3)=C2C=C1
Biological Activity
DescriptionEGFR-IN-71 is a potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 value of 3.7 μM. This compound is particularly useful in research focused on chordoma, providing a tool for studying EGFR-related signaling pathways. Additionally, EGFR-IN-71 features an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling diverse applications in chemical biology and bioconjugation studies.
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