Product Data Sheet
Erlotinib-13C6 hydrochloride
Catalog No. A28782
Erlotinib-13C6 hydrochloride is a stable isotope-labeled derivative of Erlotinib hydrochloride, targeting the epidermal growth factor receptor (EGFR) kinase with an IC50 of 2 nM. This compound serves as a valuable tool in click chemistry applications due to its alkyne group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its isotopic labeling facilitates quantitative analysis in metabolic studies and drug metabolism research.
Chemical Information
| Catalog Num | A28782 |
|---|---|
| M. Wt | 435.85 |
| Formula | C1613C6H24ClN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1210610-07-3 |
| Synonyms | CP-358774-13C6 hydrochloride; NSC 718781-13C6 hydrochloride; OSI-774-13C6 hydrochloride |
| SMILES | COCCOC(C(OCCOC)=C1)=CC2=C1C(N[13C]3=[13CH][13C](C#C)=[13CH][13CH]=[13CH]3)=NC=N2.Cl |
Biological Activity
| Description | Erlotinib-13C6 hydrochloride is a stable isotope-labeled derivative of Erlotinib hydrochloride, targeting the epidermal growth factor receptor (EGFR) kinase with an IC50 of 2 nM. This compound serves as a valuable tool in click chemistry applications due to its alkyne group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its isotopic labeling facilitates quantitative analysis in metabolic studies and drug metabolism research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
