Product Data Sheet
BPI-15086
Catalog No. A28817
BPI-15086 is an orally active, potent, irreversible inhibitor targeting the epidermal growth factor receptor (EGFR) and specifically the T790M resistance mutation. This compound exhibits significant biological activity against mutant EGFR, making it a valuable tool for research focused on non-small-cell lung cancer. Its selective action aids in the study of resistance mechanisms and therapeutic responses associated with EGFR mutations.
Chemical Information
| Catalog Num | A28817 |
|---|---|
| M. Wt | 593.08 |
| Formula | C29H33ClN8O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1644502-33-9 |
| Synonyms | |
| SMILES | ClC(C(NC1=CC=CC=C1C(C(N(C)C)=O)=O)=N2)=CN=C2NC3=CC(NC(C=C)=O)=C(N4CCN(C)CC4)C=C3OC |
Biological Activity
| Description | BPI-15086 is an orally active, potent, irreversible inhibitor targeting the epidermal growth factor receptor (EGFR) and specifically the T790M resistance mutation. This compound exhibits significant biological activity against mutant EGFR, making it a valuable tool for research focused on non-small-cell lung cancer. Its selective action aids in the study of resistance mechanisms and therapeutic responses associated with EGFR mutations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
