Product Data Sheet

Dosimertinib-d3

Catalog No. A28820

main product photo
Dosimertinib-d3 is a potent inhibitor of the epidermal growth factor receptor (EGFR). This compound effectively reduces levels of phosphorylated EGFR and ERK proteins, exhibiting significant antiproliferative and antitumor activities. Dosimertinib-d3 is particularly relevant for research applications targeting non-small-cell lung cancer (NSCLC) and offers a valuable tool for studying EGFR-mediated signaling pathways.
Chemical Information
Catalog NumA28820
M. Wt504.64
FormulaC28H28D5N7O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2403760-70-1
Synonyms
SMILES[2H]/C([2H])=C\C(NC1=CC(NC2=NC=CC(C3=CN(C4=C3C=CC=C4)C([2H])([2H])[2H])=N2)=C(C=C1N(CCN(C)C)C)OC)=O
Biological Activity
DescriptionDosimertinib-d3 is a potent inhibitor of the epidermal growth factor receptor (EGFR). This compound effectively reduces levels of phosphorylated EGFR and ERK proteins, exhibiting significant antiproliferative and antitumor activities. Dosimertinib-d3 is particularly relevant for research applications targeting non-small-cell lung cancer (NSCLC) and offers a valuable tool for studying EGFR-mediated signaling pathways.
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SHIPPING AND STORAGE
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