Product Data Sheet
EGFR-IN-103
Catalog No. A28827
EGFR-IN-103 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 value of 6 nM for phosphorylated EGFR (pEGFR). This compound demonstrates effective inhibition of EGFR-mediated signaling pathways, making it valuable in cancer research, particularly in drug resistance studies and therapeutic applications targeting EGFR-driven tumors. Its specificity and potency make it an essential tool for studying EGFR-related biological processes and evaluating new therapeutic strategies.
Chemical Information
| Catalog Num | A28827 |
|---|---|
| M. Wt | 612.51 |
| Formula | C28H24Cl2FN7O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2568506-66-9 |
| Synonyms | |
| SMILES | O=C(NC1=NC=CS1)C(N2N=C3C(C(Cl)=CC(C4=CC=C(N5CCOCC5)C=C4)=C3Cl)=C2)C6=C7N(C[C@@H](C7)F)C=N6 |
Biological Activity
| Description | EGFR-IN-103 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 value of 6 nM for phosphorylated EGFR (pEGFR). This compound demonstrates effective inhibition of EGFR-mediated signaling pathways, making it valuable in cancer research, particularly in drug resistance studies and therapeutic applications targeting EGFR-driven tumors. Its specificity and potency make it an essential tool for studying EGFR-related biological processes and evaluating new therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
