Product Data Sheet
Rezivertinib hydrochloride
Catalog No. A28839
Rezivertinib hydrochloride is a highly selective and irreversible third-generation inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It demonstrates potent activity against both the common EGFR activating mutations and the T790M resistance mutation. This compound also possesses excellent central nervous system (CNS) penetration, making it a valuable tool in the study of antitumor activity, particularly in the context of non-small cell lung cancer (NSCLC). Researchers may utilize Rezivertinib hydrochloride to investigate mechanisms of resistance and evaluate therapeutic strategies targeting EGFR-related pathways.
Chemical Information
| Catalog Num | A28839 |
|---|---|
| M. Wt | 523.03 |
| Formula | C27H31ClN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2170255-78-2 |
| Synonyms | BPI-7711 hydrochloride |
| SMILES | O=C(NC1=CC(NC2=NC(C3=CN(C)C4=C3C=CC=C4)=CC=N2)=C(C=C1OCCN(C)C)OC)C=C.Cl |
Biological Activity
| Description | Rezivertinib hydrochloride is a highly selective and irreversible third-generation inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It demonstrates potent activity against both the common EGFR activating mutations and the T790M resistance mutation. This compound also possesses excellent central nervous system (CNS) penetration, making it a valuable tool in the study of antitumor activity, particularly in the context of non-small cell lung cancer (NSCLC). Researchers may utilize Rezivertinib hydrochloride to investigate mechanisms of resistance and evaluate therapeutic strategies targeting EGFR-related pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
