Product Data Sheet
EGFR-IN-24
Catalog No. A28844
EGFR-IN-24 is a selective inhibitor of the epidermal growth factor receptor (EGFR), demonstrated to effectively target both EGFR mutations del19/T790M/C797S and L858R/T790M/C797S. This compound exhibits significant antiproliferative activity, making it a valuable tool in cancer research, particularly for studies focused on non-small cell lung cancer and resistance mechanisms associated with EGFR mutations. Researchers can utilize EGFR-IN-24 to explore therapeutic strategies and develop potential treatment options for patients harboring these challenging mutations.
Chemical Information
| Catalog Num | A28844 |
|---|---|
| M. Wt | 546.64 |
| Formula | C30H35FN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2757548-54-0 |
| Synonyms | |
| SMILES | COC1=C(C=NC=C1)C2=NC(C)=CC(C(NC3=NC4=CC(C5CCN(CC5)C)=CC=C4N3CC(C)(O)C)=O)=C2F |
Biological Activity
| Description | EGFR-IN-24 is a selective inhibitor of the epidermal growth factor receptor (EGFR), demonstrated to effectively target both EGFR mutations del19/T790M/C797S and L858R/T790M/C797S. This compound exhibits significant antiproliferative activity, making it a valuable tool in cancer research, particularly for studies focused on non-small cell lung cancer and resistance mechanisms associated with EGFR mutations. Researchers can utilize EGFR-IN-24 to explore therapeutic strategies and develop potential treatment options for patients harboring these challenging mutations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
