Product Data Sheet
Erlotinib-d6
Catalog No. A28857
Erlotinib-d6 is a deuterated analog of Erlotinib, specifically targeting the epidermal growth factor receptor (EGFR) as a tyrosine kinase inhibitor. With an IC50 of 2 nM for human EGFR, it demonstrates potent inhibitory activity crucial for studying EGFR-mediated signaling pathways. As a click chemistry reagent, Erlotinib-d6 contains an alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for applications in chemical biology and bioconjugation research.
Chemical Information
| Catalog Num | A28857 |
|---|---|
| M. Wt | 399.47 |
| Formula | C22H17D6N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1034651-23-4 |
| Synonyms | CP-358774-d6; NSC 718781-d6; OSI-774-d6 |
| SMILES | [2H]C([2H])([2H])OCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC([2H])([2H])[2H] |
Biological Activity
| Description | Erlotinib-d6 is a deuterated analog of Erlotinib, specifically targeting the epidermal growth factor receptor (EGFR) as a tyrosine kinase inhibitor. With an IC50 of 2 nM for human EGFR, it demonstrates potent inhibitory activity crucial for studying EGFR-mediated signaling pathways. As a click chemistry reagent, Erlotinib-d6 contains an alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) for applications in chemical biology and bioconjugation research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
