Epitinib succinate
Catalog No. A28879

Epitinib succinate is a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that demonstrates effective oral bioavailability and optimized penetration into the central nervous system. This compound is primarily utilized in cancer research, offering insights into targeted therapies for EGFR-associated tumors. Additionally, Epitinib succinate features an alkyne moiety that enables its use in click chemistry, specifically in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating advanced biochemical studies.
Chemical Information
| Catalog Num | A28879 |
|---|---|
| M. Wt | 548.59 |
| Formula | C28H32N6O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2252334-12-4 |
| Synonyms | HMPL-813 succinate |
| SMILES | O=C(CCC(O)=O)O.O=C(N1CCN(CC)CC1)NC2=CC3=C(NC4=CC=CC(C#C)=C4)N=CN=C3C=C2OC |
Biological Activity
| Description | Epitinib succinate is a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that demonstrates effective oral bioavailability and optimized penetration into the central nervous system. This compound is primarily utilized in cancer research, offering insights into targeted therapies for EGFR-associated tumors. Additionally, Epitinib succinate features an alkyne moiety that enables its use in click chemistry, specifically in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating advanced biochemical studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


