Product Data Sheet
Afatinib-d6
Catalog No. A28882
Afatinib-d6 is a deuterium-labeled derivative of Afatinib, an irreversible inhibitor of the epidermal growth factor receptor (EGFR) family. This stable isotope variant is utilized primarily in pharmacokinetic studies to trace the metabolic pathways of Afatinib and assess drug distribution and elimination in various biological systems. It offers valuable insights for researchers in oncology and drug development, enhancing the understanding of EGFR-targeted therapies.
Chemical Information
| Catalog Num | A28882 |
|---|---|
| M. Wt | 491.98 |
| Formula | C24H19D6ClFN5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1313874-96-2 |
| Synonyms | BIBW 2992 d6 |
| SMILES | O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H] |
Biological Activity
| Description | Afatinib-d6 is a deuterium-labeled derivative of Afatinib, an irreversible inhibitor of the epidermal growth factor receptor (EGFR) family. This stable isotope variant is utilized primarily in pharmacokinetic studies to trace the metabolic pathways of Afatinib and assess drug distribution and elimination in various biological systems. It offers valuable insights for researchers in oncology and drug development, enhancing the understanding of EGFR-targeted therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
