Product Data Sheet
Laprituximab emtansine
Catalog No. A28900
Laprituximab emtansine targets the epidermal growth factor receptor (EGFR) as an antibody-drug conjugate (ADC) incorporating the J2898A antibody linked to DM1, an anti-microtubule agent, via the SMCC thioether linker. This compound exhibits potent anti-cancer activity by delivering cytotoxic agents directly to HER1-expressing cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity. It is suitable for applications in cancer research, particularly in the study of targeted therapies and EGFR-related pathways.
Chemical Information
| Catalog Num | A28900 |
|---|---|
| M. Wt | |
| Formula | |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1622327-37-0 |
| Synonyms | IMGN-289; J2898A-SMCC-DM1 |
| SMILES | [Laprituximab emtansine] |
Biological Activity
| Description | Laprituximab emtansine targets the epidermal growth factor receptor (EGFR) as an antibody-drug conjugate (ADC) incorporating the J2898A antibody linked to DM1, an anti-microtubule agent, via the SMCC thioether linker. This compound exhibits potent anti-cancer activity by delivering cytotoxic agents directly to HER1-expressing cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity. It is suitable for applications in cancer research, particularly in the study of targeted therapies and EGFR-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
