Product Data Sheet

BBT-176

Catalog No. A28949

main product photo
BBT-176 is a potent oral inhibitor of the epidermal growth factor receptor (EGFR). It demonstrates significant inhibitory activity against various EGFR C797S mutant cell lines, making it a valuable tool for investigating resistance mechanisms in cancer therapy. This compound is widely utilized in cancer research to explore alternative treatment strategies targeting EGFR-related pathways.
Chemical Information
Catalog NumA28949
M. Wt601.16
FormulaC28H37ClN8O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2254805-44-0
Synonyms
SMILESO=S(NC1=C(NC2=NC(NC3=CC=C(N4CCC(CC4)N5CCN(CC5)C)C=C3OC)=NC=C2Cl)C=CC=C1)(C)=O
Biological Activity
DescriptionBBT-176 is a potent oral inhibitor of the epidermal growth factor receptor (EGFR). It demonstrates significant inhibitory activity against various EGFR C797S mutant cell lines, making it a valuable tool for investigating resistance mechanisms in cancer therapy. This compound is widely utilized in cancer research to explore alternative treatment strategies targeting EGFR-related pathways.
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