Product Data Sheet

OUL245

Catalog No. A28977

main product photo
OUL245 is a selective inhibitor of PARP2, exhibiting an IC50 of 44 nM. It also demonstrates inhibitory activity against other PARP family members and TNKS enzymes, with IC50 values ranging from 2.9 to 8.8 μM. This compound is valuable for research into DNA repair mechanisms and the therapeutic potential of targeting PARP enzymes in various cancer models.
Chemical Information
Catalog NumA28977
M. Wt191.21
FormulaC8H5N3OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1023814-45-0
Synonyms
SMILESC1=CC2=C(C=C1O)SC3=NN=CN23
Biological Activity
DescriptionOUL245 is a selective inhibitor of PARP2, exhibiting an IC50 of 44 nM. It also demonstrates inhibitory activity against other PARP family members and TNKS enzymes, with IC50 values ranging from 2.9 to 8.8 μM. This compound is valuable for research into DNA repair mechanisms and the therapeutic potential of targeting PARP enzymes in various cancer models.
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SHIPPING AND STORAGE
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