Product Data Sheet
PARP14 inhibitor 2
Catalog No. A28982
PARP14 Inhibitor 2 is a highly selective inhibitor targeting PARP14 with an IC50 value of less than 30 nM. This compound effectively inhibits the mono-ADP-ribosyltransferase activity of PARP14, thereby modulating signaling pathways associated with IFN-γ and IL-4. By reversing protumor macrophage polarization and inhibiting pro-inflammatory responses, PARP14 Inhibitor 2 holds promise for the investigation of diseases related to PARP14, including tumors, atopic dermatitis, and autoimmune disorders.
Chemical Information
| Catalog Num | A28982 |
|---|---|
| M. Wt | 489.60 |
| Formula | C25H32FN3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3064731-00-3 |
| Synonyms | |
| SMILES | O=C1N=C(CSC2CCOCC2)NC3=CC(OCC45CCC(CC4)(CC5)NC(C)=O)=CC(F)=C13 |
Biological Activity
| Description | PARP14 Inhibitor 2 is a highly selective inhibitor targeting PARP14 with an IC50 value of less than 30 nM. This compound effectively inhibits the mono-ADP-ribosyltransferase activity of PARP14, thereby modulating signaling pathways associated with IFN-γ and IL-4. By reversing protumor macrophage polarization and inhibiting pro-inflammatory responses, PARP14 Inhibitor 2 holds promise for the investigation of diseases related to PARP14, including tumors, atopic dermatitis, and autoimmune disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
