Product Data Sheet
ADP-ribose/PARP-IN-1
Catalog No. A28996
ADP-ribose/PARP-IN-1 is a conjugated compound that combines disease-targeting moieties with PARP inhibitor functionality. This reagent selectively delivers PARP inhibitors to tumor cells, facilitating the inhibition of PARP enzymes that are critical for DNA damage repair. The presence of a cleavable linker ensures the release of the PARP inhibitor under specific conditions, while the chelator component enables the accumulation of radionuclides that exert cytotoxic effects. ADP-ribose/PARP-IN-1 is a valuable tool for research into prostate cancer and other malignancies characterized by PARP dependency.
Chemical Information
| Catalog Num | A28996 |
|---|---|
| M. Wt | 1890.07 |
| Formula | C92H125FN16O26 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3047557-92-3 |
| Synonyms | |
| SMILES | O=C1C2=C3C(CCN1)=C(C4=CC=C(C=C4)CN(C)C(CCCCCCC(NCCCC[C@@H](NC(CCC(N5CCN(CCN(CCN(CC5)CC(O)=O)CC(O)=O)CC(O)=O)C(O)=O)=O)C(N[C@H](CC(O)=O)C(NCCC(NC[C@@H]6CC[C@H](CC6)C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC7=CC8=C(C=CC=C8)C=C7)=O)=O)=O)=O)=O)=O)NC3=CC(F)=C2 |
Biological Activity
| Description | ADP-ribose/PARP-IN-1 is a conjugated compound that combines disease-targeting moieties with PARP inhibitor functionality. This reagent selectively delivers PARP inhibitors to tumor cells, facilitating the inhibition of PARP enzymes that are critical for DNA damage repair. The presence of a cleavable linker ensures the release of the PARP inhibitor under specific conditions, while the chelator component enables the accumulation of radionuclides that exert cytotoxic effects. ADP-ribose/PARP-IN-1 is a valuable tool for research into prostate cancer and other malignancies characterized by PARP dependency. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
