Product Data Sheet

4-Aminonaphthalimide

Catalog No. A29017

main product photo
4-Aminonaphthalimide is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), a key enzyme involved in DNA repair processes. This compound enhances the cytotoxic effects of γ-radiation in cancer cells, making it a valuable tool for studies focused on cancer therapy and radiation biology. Its dual function as a PARP inhibitor and radiation sensitizer positions 4-Aminonaphthalimide as an important reagent for research applications in oncology and therapeutic resistance.
Chemical Information
Catalog NumA29017
M. Wt212.20
FormulaC12H8N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1742-95-6
Synonyms
SMILESO=C1NC(C2=CC=C(N)C3=CC=CC1=C23)=O
Biological Activity
Description4-Aminonaphthalimide is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), a key enzyme involved in DNA repair processes. This compound enhances the cytotoxic effects of γ-radiation in cancer cells, making it a valuable tool for studies focused on cancer therapy and radiation biology. Its dual function as a PARP inhibitor and radiation sensitizer positions 4-Aminonaphthalimide as an important reagent for research applications in oncology and therapeutic resistance.
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