Product Data Sheet

PARP1-IN-51

Catalog No. A29018

main product photo
PARP1-IN-51 is a potent inhibitor of the enzyme PARP1, which plays a critical role in DNA repair mechanisms. This compound exhibits significant biological activity by disrupting the PARP1-mediated repair of single-strand breaks, ultimately leading to cancer cell apoptosis. PARP1-IN-51 is particularly valuable for research in oncology, including studies focused on breast cancer and other malignancies with defective DNA repair pathways.
Chemical Information
Catalog NumA29018
M. Wt443.43
FormulaC21H20F3N7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3017165-87-3
Synonyms
SMILESCC1=NC2=C(C(F)=C(C=C2)CN3CCN(CC3)C4=CN5C=C(N=C5C=N4)C(F)F)NC1=O
Biological Activity
DescriptionPARP1-IN-51 is a potent inhibitor of the enzyme PARP1, which plays a critical role in DNA repair mechanisms. This compound exhibits significant biological activity by disrupting the PARP1-mediated repair of single-strand breaks, ultimately leading to cancer cell apoptosis. PARP1-IN-51 is particularly valuable for research in oncology, including studies focused on breast cancer and other malignancies with defective DNA repair pathways.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.