PARP7-IN-24
Catalog No. A29022

PARP7-IN-24 is a highly potent inhibitor of PARP7, exhibiting an EC50 of 0.375 nM for pSTAT1 in NCI-H1373 cells. This compound is poised for significant contributions to cancer research, facilitating the study of PARP7's role in tumor biology and potential therapeutic interventions. Its strong inhibitory activity makes it a valuable tool for exploring the molecular mechanisms underlying cancer progression and treatment responses.
Chemical Information
| Catalog Num | A29022 |
|---|---|
| M. Wt | 555.43 |
| Formula | C24H19F6N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3072866-54-4 |
| Synonyms | |
| SMILES | O=C1NN=CC(O[C@@H](C)C[C@H](CN2C(C(C(F)=C(F)C(C3=NC=C(OC)C=N3)=C4)=C4C=C2)=O)F)=C1C(F)(F)F |
Biological Activity
| Description | PARP7-IN-24 is a highly potent inhibitor of PARP7, exhibiting an EC50 of 0.375 nM for pSTAT1 in NCI-H1373 cells. This compound is poised for significant contributions to cancer research, facilitating the study of PARP7's role in tumor biology and potential therapeutic interventions. Its strong inhibitory activity makes it a valuable tool for exploring the molecular mechanisms underlying cancer progression and treatment responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


