Product Data Sheet

PARP-2/1-IN-2

Catalog No. A29027

main product photo
PARP-2/1-IN-2 is a potent inhibitor of poly (ADP-ribose) polymerases 1 and 2, exhibiting Kis of 2 nM and 5 nM, respectively. It demonstrates a biological activity with an EC50 of 3 nM in cell-based assays assessing PARP activity. This compound is valuable for research focused on cancer therapeutics, DNA repair mechanisms, and the role of PARP in various cellular processes.
Chemical Information
Catalog NumA29027
M. Wt244.29
FormulaC13H16N4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.912444-01-0
Synonyms
SMILESNC(C1=C2C(N=C([C@]3(C)CCCN3)N2)=CC=C1)=O
Biological Activity
DescriptionPARP-2/1-IN-2 is a potent inhibitor of poly (ADP-ribose) polymerases 1 and 2, exhibiting Kis of 2 nM and 5 nM, respectively. It demonstrates a biological activity with an EC50 of 3 nM in cell-based assays assessing PARP activity. This compound is valuable for research focused on cancer therapeutics, DNA repair mechanisms, and the role of PARP in various cellular processes.
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