Product Data Sheet

Acetaminophen-13C6

Catalog No. A29150

main product photo
Acetaminophen-13C6 is a stable isotope-labeled derivative of acetaminophen, primarily utilized for metabolic studies and tracing experiments. This compound functions as a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 25.8 μM, demonstrating significant antipyretic and analgesic properties. Additionally, it acts as a potent inhibitor of hepatic N-acetyltransferase 2 (NAT2), making it valuable for pharmacokinetic research and understanding drug metabolism.
Chemical Information
Catalog NumA29150
M. Wt157.12
FormulaC213C6H9NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2132405-57-1
SynonymsParacetamol-13C6; 4-Acetamidophenol-13C6; 4'-Hydroxyacetanilide-13C6
SMILESCC(N[13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)O)=O
Biological Activity
DescriptionAcetaminophen-13C6 is a stable isotope-labeled derivative of acetaminophen, primarily utilized for metabolic studies and tracing experiments. This compound functions as a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 25.8 μM, demonstrating significant antipyretic and analgesic properties. Additionally, it acts as a potent inhibitor of hepatic N-acetyltransferase 2 (NAT2), making it valuable for pharmacokinetic research and understanding drug metabolism.
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