Acetaminophen-13C6
Catalog No. A29150

Acetaminophen-13C6 is a stable isotope-labeled derivative of acetaminophen, primarily utilized for metabolic studies and tracing experiments. This compound functions as a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 25.8 μM, demonstrating significant antipyretic and analgesic properties. Additionally, it acts as a potent inhibitor of hepatic N-acetyltransferase 2 (NAT2), making it valuable for pharmacokinetic research and understanding drug metabolism.
Chemical Information
| Catalog Num | A29150 |
|---|---|
| M. Wt | 157.12 |
| Formula | C213C6H9NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2132405-57-1 |
| Synonyms | Paracetamol-13C6; 4-Acetamidophenol-13C6; 4'-Hydroxyacetanilide-13C6 |
| SMILES | CC(N[13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)O)=O |
Biological Activity
| Description | Acetaminophen-13C6 is a stable isotope-labeled derivative of acetaminophen, primarily utilized for metabolic studies and tracing experiments. This compound functions as a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 25.8 μM, demonstrating significant antipyretic and analgesic properties. Additionally, it acts as a potent inhibitor of hepatic N-acetyltransferase 2 (NAT2), making it valuable for pharmacokinetic research and understanding drug metabolism. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


