Product Data Sheet

WIZ degrader 8

Catalog No. A29195

main product photo
WIZ degrader 8 is a selective degrader targeting the transcription factor WIZ, promoting the degradation of WIZ and subsequently inducing the expression of fetal hemoglobin (HbF). This compound has significant potential for research applications related to sickle cell disease, as it may serve as a therapeutic strategy to modulate HbF levels and alleviate disease symptoms.
Chemical Information
Catalog NumA29195
M. Wt385.46
FormulaC21H27N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2879251-26-8
Synonyms
SMILESO=C1N(C2C(NC(CC2)=O)=O)CC3=CC(O[C@H]4CN(C[C@@H](C4)C)CC)=CC=C31
Biological Activity
DescriptionWIZ degrader 8 is a selective degrader targeting the transcription factor WIZ, promoting the degradation of WIZ and subsequently inducing the expression of fetal hemoglobin (HbF). This compound has significant potential for research applications related to sickle cell disease, as it may serve as a therapeutic strategy to modulate HbF levels and alleviate disease symptoms.
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