Product Data Sheet
Ep300/CREBBP-IN-3
Catalog No. A29228
Ep300/CREBBP-IN-3 is a potent inhibitor of the Ep300 and CREBBP enzymes, demonstrating IC50 values of 0.056 μM and 0.095 μM, respectively. This compound is primarily utilized in cancer research, facilitating investigations into the role of histone acetylation in tumor progression and therapy resistance. Its ability to selectively inhibit these acetyltransferases makes it a valuable tool for understanding the epigenetic regulation of gene expression in oncology.
Chemical Information
| Catalog Num | A29228 |
|---|---|
| M. Wt | 531.50 |
| Formula | C26H25F4N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2259641-47-7 |
| Synonyms | |
| SMILES | O=C([C@@H]1N(C(C2(C3=CC=C(C(C(F)(F)F)=O)C=C3)CCCCC2)=O)C[C@H](F)C1)NC4=CC=C(NN=C5)C5=N4 |
Biological Activity
| Description | Ep300/CREBBP-IN-3 is a potent inhibitor of the Ep300 and CREBBP enzymes, demonstrating IC50 values of 0.056 μM and 0.095 μM, respectively. This compound is primarily utilized in cancer research, facilitating investigations into the role of histone acetylation in tumor progression and therapy resistance. Its ability to selectively inhibit these acetyltransferases makes it a valuable tool for understanding the epigenetic regulation of gene expression in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
