Product Data Sheet
GSK-J1 sodium
Catalog No. A29243
GSK-J1 sodium is a selective inhibitor of the histone demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 value of 60 nM for KDM6B. This compound modulates H3K27me3/me2 levels, thereby influencing gene expression and cellular differentiation. GSK-J1 sodium is useful in research applications focused on epigenetic regulation, cancer biology, and developmental processes.
Chemical Information
| Catalog Num | A29243 |
|---|---|
| M. Wt | 411.43 |
| Formula | C22H22N5NaO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1797832-71-3 |
| Synonyms | |
| SMILES | O=C(CCNC1=CC(N2CCC3=C(CC2)C=CC=C3)=NC(C4=CC=CC=N4)=N1)O[Na] |
Biological Activity
| Description | GSK-J1 sodium is a selective inhibitor of the histone demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 value of 60 nM for KDM6B. This compound modulates H3K27me3/me2 levels, thereby influencing gene expression and cellular differentiation. GSK-J1 sodium is useful in research applications focused on epigenetic regulation, cancer biology, and developmental processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
