Product Data Sheet

LSD1-IN-46

Catalog No. A29255

main product photo
LSD1-IN-46 is a potent and orally bioavailable inhibitor of Lysine-specific demethylase 1 (LSD1), exhibiting an IC50 of 0.082 μM. By disrupting the β-catenin-mediated transcriptional program, LSD1-IN-46 effectively diminishes the stemness characteristics of gastric cancer cells. This compound demonstrates significant anti-tumor activity, making it a valuable reagent for research into gastric cancer therapeutics.
Chemical Information
Catalog NumA29255
M. Wt351.49
FormulaC22H29N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2982716-97-0
Synonyms
SMILESCN(C)C(CC1)CCN1CCCN2C3=C(C=CC=C3)OC4=CC=CC=C24
Biological Activity
DescriptionLSD1-IN-46 is a potent and orally bioavailable inhibitor of Lysine-specific demethylase 1 (LSD1), exhibiting an IC50 of 0.082 μM. By disrupting the β-catenin-mediated transcriptional program, LSD1-IN-46 effectively diminishes the stemness characteristics of gastric cancer cells. This compound demonstrates significant anti-tumor activity, making it a valuable reagent for research into gastric cancer therapeutics.
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