Product Data Sheet
α-Hydroxyglutaric acid-13C5 disodium
Catalog No. A29266
α-Hydroxyglutaric acid-13C5 disodium is a stable isotope-labeled form of α-Hydroxyglutaric acid, an α-hydroxy acid derived from glutaric acid. This compound acts as a competitive inhibitor of various α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methylcytosine hydroxylases. It is useful in research applications involving epigenetics, metabolism studies, and cellular response to metabolic changes.
Chemical Information
| Catalog Num | A29266 |
|---|---|
| M. Wt | 197.04 |
| Formula | 13C5H6Na2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2482467-23-0 |
| Synonyms | 2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 sodium; 2-Hydroxypentanedioic acid-13C5 disodium |
| SMILES | O=[13C](O[Na])[13CH2][13CH2][13CH](O)[13C](O[Na])=O |
Biological Activity
| Description | α-Hydroxyglutaric acid-13C5 disodium is a stable isotope-labeled form of α-Hydroxyglutaric acid, an α-hydroxy acid derived from glutaric acid. This compound acts as a competitive inhibitor of various α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methylcytosine hydroxylases. It is useful in research applications involving epigenetics, metabolism studies, and cellular response to metabolic changes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
