Product Data Sheet
INCB059872 tosylate
Catalog No. A29301
INCB059872 tosylate is a potent, selective inhibitor of lysine-specific demethylase 1 (LSD1). By binding to and inhibiting LSD1, this compound enhances H3K4 methylation, which increases the expression of tumor suppressor genes. Additionally, the inhibition of LSD1 promotes H3K9 methylation, leading to a decrease in the transcription of genes associated with tumor promotion. Its properties make INCB059872 tosylate valuable for research on epigenetic regulation and cancer therapy.
Chemical Information
| Catalog Num | A29301 |
|---|---|
| M. Wt | 558.73 |
| Formula | C30H42N2O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2081940-67-0 |
| Synonyms | |
| SMILES | OC(C1(CCC1)CN2CCC(COC)(CC2)CN[C@H]3[C@@](C4=CC=CC=C4)([H])C3)=O.O=S(O)(C5=CC=C(C=C5)C)=O |
Biological Activity
| Description | INCB059872 tosylate is a potent, selective inhibitor of lysine-specific demethylase 1 (LSD1). By binding to and inhibiting LSD1, this compound enhances H3K4 methylation, which increases the expression of tumor suppressor genes. Additionally, the inhibition of LSD1 promotes H3K9 methylation, leading to a decrease in the transcription of genes associated with tumor promotion. Its properties make INCB059872 tosylate valuable for research on epigenetic regulation and cancer therapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
