Product Data Sheet
S1427
Catalog No. A29303
S1427 is a tranylcypromine-derived inhibitor of lysine-specific demethylase 1 (LSD1) with an IC50 of 390 nM and a Ki of 80 nM. This compound demonstrates selective inhibition of the hERG channel and displays favorable microsomal stability profiles. S1427 has been shown to partially reduce the proliferation of cancer cells, making it a valuable tool for research in cancer biology and epigenetic regulation.
Chemical Information
| Catalog Num | A29303 |
|---|---|
| M. Wt | 474.52 |
| Formula | C25H29F3N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2447061-40-5 |
| Synonyms | |
| SMILES | O=C(N1CCC2(CC1)CCNC2)CN[C@H]3C[C@@H]3C4=C(C(F)=CC(F)=C4)OCC5=CC=CN=C5F |
Biological Activity
| Description | S1427 is a tranylcypromine-derived inhibitor of lysine-specific demethylase 1 (LSD1) with an IC50 of 390 nM and a Ki of 80 nM. This compound demonstrates selective inhibition of the hERG channel and displays favorable microsomal stability profiles. S1427 has been shown to partially reduce the proliferation of cancer cells, making it a valuable tool for research in cancer biology and epigenetic regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
