Product Data Sheet
LSD1-IN-18
Catalog No. A29313
LSD1-IN-18 is a selective, non-covalent inhibitor of LSD1, exhibiting a Ki of 0.156 μM and a KD of 0.075 μM. It demonstrates significant antiproliferative effects in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with calculated IC50 values of 0.16 μM and 0.21 μM, respectively, after 72 hours of treatment. This compound provides a valuable tool for investigating the role of LSD1 in cancer biology and therapeutic applications.
Chemical Information
| Catalog Num | A29313 |
|---|---|
| M. Wt | 528.69 |
| Formula | C31H40N6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2983011-61-4 |
| Synonyms | |
| SMILES | COC1=CC2=C(C(NC3CCN(CC3)CC4=CC=C5C=CC=CC5=C4)=NC(NCCCN(C)C)=N2)C=C1OC |
Biological Activity
| Description | LSD1-IN-18 is a selective, non-covalent inhibitor of LSD1, exhibiting a Ki of 0.156 μM and a KD of 0.075 μM. It demonstrates significant antiproliferative effects in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with calculated IC50 values of 0.16 μM and 0.21 μM, respectively, after 72 hours of treatment. This compound provides a valuable tool for investigating the role of LSD1 in cancer biology and therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
