Product Data Sheet

Setiptiline-d3

Catalog No. A29351

main product photo
Setiptiline-d3 is a deuterium-labeled analog of Setiptiline, a tetracyclic antidepressant functioning primarily as a noradrenergic and specific serotonergic antidepressant. Its mechanism involves norepinephrine reuptake inhibition and antagonism of α2-adrenergic and various serotonin receptors, including 5-HT2A, 5-HT2C, and 5-HT3 subtypes, in addition to H1 receptor inverse agonism. This stable isotope variant is valuable for tracing studies in pharmacokinetics and elucidating the pharmacodynamics of Setiptiline in clinical research.
Chemical Information
Catalog NumA29351
M. Wt264.38
FormulaC19H16D3N
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1795024-97-3
Synonyms
SMILESC(N1CC2=C(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1)([2H])([2H])[2H]
Biological Activity
DescriptionSetiptiline-d3 is a deuterium-labeled analog of Setiptiline, a tetracyclic antidepressant functioning primarily as a noradrenergic and specific serotonergic antidepressant. Its mechanism involves norepinephrine reuptake inhibition and antagonism of α2-adrenergic and various serotonin receptors, including 5-HT2A, 5-HT2C, and 5-HT3 subtypes, in addition to H1 receptor inverse agonism. This stable isotope variant is valuable for tracing studies in pharmacokinetics and elucidating the pharmacodynamics of Setiptiline in clinical research.
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